Multiplexed CRISPR Assay for Amplification-Free Detection of miRNAs

Multiplexed CRISPR Assay for Amplification-Free Detection of miRNAs

CRISPR-Cas proteins from bacteria are powerful tools for gene editing and molecular diagnostics. Expanding capacity of CRISPR to low cost, multiplexed assays of biomarkers is a key to future disease diagnostics, since multiple biomarker detection is essential for reliable diagnostics. Herein we desc...

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Bibliographic Details
Main Authors: P. I. Thilini De Silva, Keshani Hiniduma, Rachelle Canete, Ketki S. Bhalerao, Sherif M. Shawky, Hansana Gunathilaka, Jessica L. Rouge, Islam M. Mosa, David C. Steffens, Kevin Manning, Breno S. Diniz, James F. Rusling
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Biosensors
Subjects:
CRISPR
Alzheimer biomarkers
miRNAs
multiplexed assay
fluorescence
Online Access:https://www.mdpi.com/2079-6374/15/6/346
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