Drug Repurposing to Inhibit Oncostatin M in Crohn’s Disease

Drug Repurposing to Inhibit Oncostatin M in Crohn’s Disease

Crohn’s disease is an inflammatory bowel disease (IBD) that currently lacks satisfactory treatment options. Therefore, new targets for new drugs are urgently needed to combat this disease. In the present study, we investigated the transcriptomics-based mRNA expression of intestinal biopsies from pat...

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Main Authors: Faranak Bahramimehr, Axel Guthart, Stefanie Kurz, Yuanping Hai, Mona Dawood, Rümeysa Yücer, Nasim Shahhamzehei, Ralf Weiskirchen, Wilfried Roth, Wolfgang Stremmel, Gerhard Bringmann, Thomas Efferth
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Molecules
Subjects:
chronic inflammation
inflammatory bowel disease
microscale thermophoresis
molecular docking
transcriptomics
virtual drug screening
Online Access:https://www.mdpi.com/1420-3049/30/9/1897
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