An Engineered RNase P Ribozyme Effectively Reduces Human Coronavirus 229E Gene Expression and Growth in Human Cells

The human coronavirus 229E (HCoV-229E) is a member of the human coronavirus family that includes SARS-CoV-2, the causative agent of COVID-19. Developing antiviral strategies and compounds is crucial to treat and prevent HCoV-229E infections and the associated diseases. Ribozymes derived from ribonuc...

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Bibliographic Details
Main Authors: Yujun Liu, Bin Yan, Hao Gong, Fenyong Liu
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Zoonotic Diseases
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Online Access:https://www.mdpi.com/2813-0227/5/2/12
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