Antioxidant Peptides from the Fruit Source of the Oil Crop <i>Litsea cubeba</i> Ameliorate FFA-Induced Oxidative Stress Injury: Based on Nrf2/Keap1 Pathway and Molecular Dynamics Simulations

Antioxidant Peptides from the Fruit Source of the Oil Crop <i>Litsea cubeba</i> Ameliorate FFA-Induced Oxidative Stress Injury: Based on Nrf2/Keap1 Pathway and Molecular Dynamics Simulations

In this study, we systematically investigated the mechanisms of the antioxidation and anti-lipid accumulation effects of antioxidant peptides from <i>Litsea cubeba</i> on a free fatty acid (FFA)-induced NAFLD model of HepG2 cells. The NAFLD cell model was constructed by inducing the HepG...

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Bibliographic Details
Main Authors: Li Li, Ying Hu, Yu-Mei Wang, Xiao-Xue Wu, Si-Tong Lin, Hang Li, Ji Zhang, Guo-Rong Fan, Zong-De Wang, Bin Wang, Shang-Xing Chen
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Foods
Subjects:
<i>Litsea cubeba</i> antioxidant peptides
ROS
Keap1/Nrf2 pathway
molecular docking
molecular dynamics simulations
Online Access:https://www.mdpi.com/2304-8158/14/10/1707
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