Reliability of clinical impressions and optimal genetic diagnostic strategies of heritable connective tissue disorders with ocular involvement in a large Chinese cohort

Abstract Purpose This study aimed to elucidate the reliability of clinical impressions based on ocular manifestations in patients suspected of heritable connective tissue disorders (HCTDs) compared to the final genetic diagnosis. Furthermore, it sought to determine the optimal diagnostic strategy fo...

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Bibliographic Details
Main Authors: Qin-Meng Shu, Yu-Qiao Ju, Yuan Zong, Ting Zhang, Xin Huang, Feng-juan Gao, Qing Chang
Format: Article
Language:English
Published: BMC 2025-04-01
Series:Human Genomics
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Online Access:https://doi.org/10.1186/s40246-025-00749-2
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