Brain-derived uroguanylin as a regulator of postprandial brown adipose tissue activation: a potential therapeutic approach for metabolic disorders

Brain-derived uroguanylin as a regulator of postprandial brown adipose tissue activation: a potential therapeutic approach for metabolic disorders

BackgroundPreclinical and clinical research of insulin resistance and glucose homeostasis in metabolic disorders are essential. In this study, we aim to determine the expression of uroguanylin (UGN) in the mouse and human brain, its regulatory mechanisms, and its significance to patients with obesit...

Full description

Saved in:
Bibliographic Details
Main Authors: Nikola Habek, Martina Ratko, Dora Sedmak, Ivan Banovac, Vladiana Crljen, Milan Kordić, Marina Radmilović, Siniša Škokić, Martina Tkalčić, Anton Mažuranić, Pero Bubalo, Petar Škavić, Spomenka Ljubić, Dario Rahelić, Aleksandra Dugandžić
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Pharmacology
Subjects:
mouse and human brain
hypothalamus
prefrontal cortex
obesity
type 2 diabetes
glucose homeostasis
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1569163/full
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2025.1569163/full

Similar Items