Plasma metabolic profiles in alcohol use disorder: diagnostic role of arginine and emotional implications of N6-acetyl-lysine and succinic acid

Plasma metabolic profiles in alcohol use disorder: diagnostic role of arginine and emotional implications of N6-acetyl-lysine and succinic acid

Abstract Background Alcohol Use Disorder (AUD) poses a significant global health burden, yet its metabolic underpinnings remain poorly understood. The negative affective states that emerge during withdrawal drive relapse to alcohol-seeking behavior, highlighting the need for precise diagnostic crite...

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Main Authors: Guoxin Cao, Bingqing Chen, Yu Sun, Jiansheng Qiao, Tianhao Liu, Jiawei Hou, Xiaojiao Han, Ying Tang, Yixin Fu, Jiang-Hong Ye, Qingfeng Shen, Rao Fu
Format: Article
Language:English
Published: BMC 2025-06-01
Series:BMC Psychiatry
Subjects:
AUD
Negative affective state
Withdrawal
Metabolomics
Machine learning
Arginine
Online Access:https://doi.org/10.1186/s12888-025-07014-9
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https://doi.org/10.1186/s12888-025-07014-9

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