Assessment of Culture-Negative Neonatal Early-Onset Sepsis: Risk Factors and Utility of Currently Used Serum Biomarkers

Assessment of Culture-Negative Neonatal Early-Onset Sepsis: Risk Factors and Utility of Currently Used Serum Biomarkers

Introduction: Neonatal sepsis is a severe and life-threatening condition caused by pathogens in the systemic circulation within the first 28 days of life. The classical definition of neonatal sepsis implies positive central cultures, but recent findings discuss culture-negative sepsis (clinical seps...

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Main Authors: Diana Iulia Vasilescu, Adriana Mihaela Dan, Laura Andreea Stefan, Sorin Liviu Vasilescu, Vlad Dima, Monica Mihaela Cîrstoiu
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Children
Subjects:
culture-negative early neonatal sepsis
risk factors
C-reactive protein
biomarkers
antibiotic stewardship
Online Access:https://www.mdpi.com/2227-9067/12/3/355
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