An eco-friendly chemometrics assisted UV spectrophotometric method for simultaneous determination of sofosbuvir, simeprevir and ledipasvir in pharmaceuticals

Abstract This study develops and validates an eco-friendly ultraviolet (UV)-spectrophotometric method employing augmented least squares chemometric models for the simultaneous determination of three hepatitis C antiviral drugs—sofosbuvir, simeprevir, and ledipasvir. Two multivariate approaches were...

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Bibliographic Details
Main Authors: Adil Alshehri, Ali Alqahtani, Abdulrhman Alsayari, Ahmed A. Almrasy
Format: Article
Language:English
Published: BMC 2025-06-01
Series:BMC Chemistry
Subjects:
Online Access:https://doi.org/10.1186/s13065-025-01528-9
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