Estimating treatment sensitivity in synthetic and in vitro tumors using a random differential equation model
Abstract Resistance to treatment, which comes from the heterogeneity of cell types within tumors, is a leading cause of poor treatment outcomes in cancer patients. Previous mathematical work modeling cancer over time has neither emphasized the relationship between cell heterogeneity and treatment re...
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| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-05-01
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| Series: | npj Systems Biology and Applications |
| Online Access: | https://doi.org/10.1038/s41540-025-00530-0 |
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