STAU1 exhibits oncogenic characteristics and modulates alternative splicing and gene expression in lung adenocarcinoma cells

STAU1 exhibits oncogenic characteristics and modulates alternative splicing and gene expression in lung adenocarcinoma cells

Abstract Staufen double-stranded RNA-binding protein 1 (STAU1) plays a significant role in cancer development and is associated with survival outcomes in patients with lung cancer. However, its specific functions and molecular mechanisms in lung adenocarcinoma (LUAD) remain underexplored. We conduct...

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Bibliographic Details
Main Authors: Ling Zhang, Zhen Peng, Wei Ding, Haixia Wu, Rong Guo, Dewei Li, Ling Niu, Xuemei Wei
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Scientific Reports
Subjects:
STAU1
Lung adenocarcinoma
Cell adhesion
Cell cycle
Alternative splicing
RNA-seq
Online Access:https://doi.org/10.1038/s41598-025-01883-6
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https://doi.org/10.1038/s41598-025-01883-6

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