Gut commensal Alistipes shahii improves experimental colitis in mice with reduced intestinal epithelial damage and cytokine secretion

Gut commensal Alistipes shahii improves experimental colitis in mice with reduced intestinal epithelial damage and cytokine secretion

ABSTRACT The commensal bacterium Alistipes shahii is a core microbe of the human gut microbiome and its abundance is negatively correlated with inflammatory bowel diseases (IBDs). However, its fundamental role in regulating inflammatory response remains unknown. Using a dextran sulfate sodium (DSS)-...

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Bibliographic Details
Main Authors: Xiaoying Lin, Mingchao Xu, Ruiting Lan, Dalong Hu, Suping Zhang, Shuwei Zhang, Yao Lu, Hui Sun, Jing Yang, Liyun Liu, Jianguo Xu
Format: Article
Language:English
Published: American Society for Microbiology 2025-03-01
Series:mSystems
Subjects:
Alistipes shahii
inflammatory bowel diseases
short-chain fatty acids
inflammatory cytokines
mTOR
Online Access:https://journals.asm.org/doi/10.1128/msystems.01607-24
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https://journals.asm.org/doi/10.1128/msystems.01607-24

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