Turning Cancer Immunotherapy to the Emerging Immune Checkpoint TIGIT: Will This Break Through the Limitations of the Legacy Approach?

The discovery of immune checkpoints (ICs) has pushed cancer treatment into the next era. As an emerging immune checkpoint, the TIGIT/CD155 axis inhibits the cytotoxicity of T and NK cells through multiple pathways. Immune checkpoint inhibitors (ICIs) targeting TIGIT are hopefully expected to address...

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Bibliographic Details
Main Authors: Haozhe Cui, Eyad Elkord
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Vaccines
Subjects:
Online Access:https://www.mdpi.com/2076-393X/12/12/1306
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