Advances in gasdermin activation, regulation, and targeted drug development

Proteins of the gasdermin family are executors of pyroptosis. Upon cleavage-dependent/independent activation, gasdermins form pores on the cell membrane, which damage the integrity of the cell membrane and lead to pro-inflammatory cellular content release and lytic cell death. The role of gasdermin...

Full description

Saved in:
Bibliographic Details
Main Authors: Tai Luo, Yusong R. Guo
Format: Article
Language:English
Published: Compuscript Ltd 2025-06-01
Series:Acta Materia Medica
Subjects:
Online Access:https://www.scienceopen.com/hosted-document?doi=10.15212/AMM-2025-0014
Tags: Add Tag
No Tags, Be the first to tag this record!