The dysfunction of complement and coagulation in diseases: the implications for the therapeutic interventions

The dysfunction of complement and coagulation in diseases: the implications for the therapeutic interventions

Abstract The complement system, comprising over 30 proteins, is integral to the immune system, and the coagulation system is critical for vascular homeostasis. The activation of the complement and coagulation systems involves an organized proteolytic cascade, and the overactivation of these systems...

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Main Authors: Honghong Jiang, Yiming Guo, Qihang Wang, Yiran Wang, Dingchuan Peng, Yigong Fang, Lei Yan, Zhuolin Ruan, Sheng Zhang, Yong Zhao, Wendan Zhang, Wei Shang, Zhichun Feng
Format: Article
Language:English
Published: Wiley 2024-11-01
Series:MedComm
Subjects:
coagulation
complement system
immune response
inflammatory network
sepsis
Online Access:https://doi.org/10.1002/mco2.785
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https://doi.org/10.1002/mco2.785

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