The Janus Face of Oxidative Stress and Hydrogen Sulfide: Insights into Neurodegenerative Disease Pathogenesis

The Janus Face of Oxidative Stress and Hydrogen Sulfide: Insights into Neurodegenerative Disease Pathogenesis

Oxidative stress plays an essential role in neurodegenerative pathophysiology, acting as both a critical signaling mediator and a driver of neuronal damage. Hydrogen sulfide (H<sub>2</sub>S), a versatile gasotransmitter, exhibits a similarly “Janus-faced” nature, acting as a potent antio...

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Bibliographic Details
Main Authors: Constantin Munteanu, Anca Irina Galaction, Gelu Onose, Marius Turnea, Mariana Rotariu
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Antioxidants
Subjects:
oxidative stress
hydrogen sulfide (H<sub>2</sub>S)
neurodegenerative diseases
redox signaling
Janus face
neuroinflammation
Online Access:https://www.mdpi.com/2076-3921/14/3/360
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