Decentralized Point-of-Care Manufacturing of CD19 Chimeric Antigen Receptor T Cells in Mexico

Decentralized Point-of-Care Manufacturing of CD19 Chimeric Antigen Receptor T Cells in Mexico

PURPOSETo validate and replicate an automated decentralized CD19 chimeric antigen receptor T (CAR-T) cell manufacturing process from healthy adult volunteers in an academic institution in a middle-income country.METHODSHealthy volunteers were recruited and underwent leukapheresis with the continuous...

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Main Authors: Rosario Salazar-Riojas, Dalila M. Alvarado-Navarro, Yair O. Chávez-Estrada, Ana K. Hernández-Navarro, Martha B. Ake-Uc, Nidia K. Moncada-Saucedo, José C. Jaime-Pérez, Sofía I. Quezada-Ramírez, Anna C. Rodriguez-Zuñiga, David Gómez-Almaguer, Andrés Gómez-De León
Format: Article
Language:English
Published: American Society of Clinical Oncology 2025-04-01
Series:JCO Global Oncology
Online Access:https://ascopubs.org/doi/10.1200/GO-24-00581
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https://ascopubs.org/doi/10.1200/GO-24-00581

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