Biological and prognostic insights into the prostaglandin D2 signaling axis in lung adenocarcinoma

Biological and prognostic insights into the prostaglandin D2 signaling axis in lung adenocarcinoma

BackgroundTumor metabolism reprogramming is a hallmark of cancer, but metabolite-mediated intercellular communication remains poorly understood. To address this gap, we estimated and explored communication events exploring based on single‐cell RNA data, to explore the metabolic landscape of tumor mi...

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Main Authors: Qiang Liu, Huiguo Chen, Dongfang Tang, Huibiao Zhang, Shaogeng Chen, Yiran Meng, Boying Zheng, Fei Liu, Jing Zhou, Wen Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Pharmacology
Subjects:
metabolic signaling
lung adenocarcinoma
prostaglandin D2
CX3CR1+ NK/t cells
prognostic model
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1562261/full
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https://www.frontiersin.org/articles/10.3389/fphar.2025.1562261/full

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