oxLDL Downregulates the Dendritic Cell Homing Factors CCR7 and CCL21

oxLDL Downregulates the Dendritic Cell Homing Factors CCR7 and CCL21

Introduction. Dendritic cells (DCs) and oxLDL play an important role in the atherosclerotic process with DCs accumulating in the plaques during plaque progression. Our aim was to investigate the role of oxLDL in the modulation of the DC homing-receptor CCR7 and endothelial-ligand CCL21. Methods and...

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Main Authors: Thomas Nickel, Susanne Pfeiler, Claudia Summo, Reinhard Kopp, Georgios Meimarakis, Zeljka Sicic, Marius Lambert, Korbinian Lackermair, Robert David, Andres Beiras-Fernandez, Ingo Kaczmarek, Michael Weis
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/2012/320953
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http://dx.doi.org/10.1155/2012/320953

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