Gabapentin Decreases Morphine Consumption and Improves Functional Recovery following Total Knee Arthroplasty

BACKGROUND: Moderate to severe pain after total knee arthroplasty often interferes with postoperative rehabilitation and delays discharge from hospital. The present study examined the effects of a four-day postoperative gabapentin (GBP) regimen versus placebo on opioid consumption, pain scores and k...

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Main Authors: Hance Clarke, Sara Pereira, Deborah Kennedy, Ian Gilron, Joel Katz, Jeffrey Gollish, Joseph Kay
Format: Article
Language:English
Published: Wiley 2009-01-01
Series:Pain Research and Management
Online Access:http://dx.doi.org/10.1155/2009/930609
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author Hance Clarke
Sara Pereira
Deborah Kennedy
Ian Gilron
Joel Katz
Jeffrey Gollish
Joseph Kay
author_facet Hance Clarke
Sara Pereira
Deborah Kennedy
Ian Gilron
Joel Katz
Jeffrey Gollish
Joseph Kay
author_sort Hance Clarke
collection DOAJ
description BACKGROUND: Moderate to severe pain after total knee arthroplasty often interferes with postoperative rehabilitation and delays discharge from hospital. The present study examined the effects of a four-day postoperative gabapentin (GBP) regimen versus placebo on opioid consumption, pain scores and knee flexion, as well as adverse effects, after total knee arthroplasty.
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institution Kabale University
issn 1203-6765
language English
publishDate 2009-01-01
publisher Wiley
record_format Article
series Pain Research and Management
spelling doaj-art-9a5a9ed5f7954fe8bebabdd70ddc772c2025-02-03T05:46:51ZengWileyPain Research and Management1203-67652009-01-0114321722210.1155/2009/930609Gabapentin Decreases Morphine Consumption and Improves Functional Recovery following Total Knee ArthroplastyHance Clarke0Sara Pereira1Deborah Kennedy2Ian Gilron3Joel Katz4Jeffrey Gollish5Joseph Kay6Department of Anesthesia and Pain Management, Toronto General Hospital, Toronto, CanadaHolland Orthopedic and Arthritic Centre, Sunnybrook Health Sciences Centre, Toronto, CanadaHolland Orthopedic and Arthritic Centre, Sunnybrook Health Sciences Centre, Toronto, CanadaDepartments of Anesthesiology and Pharmacology & Toxicology, Queen’s University, Kingston, CanadaDepartment of Anesthesia and Pain Management, Toronto General Hospital, Toronto, CanadaHolland Orthopedic and Arthritic Centre, Sunnybrook Health Sciences Centre, Toronto, CanadaHolland Orthopedic and Arthritic Centre, Sunnybrook Health Sciences Centre, Toronto, CanadaBACKGROUND: Moderate to severe pain after total knee arthroplasty often interferes with postoperative rehabilitation and delays discharge from hospital. The present study examined the effects of a four-day postoperative gabapentin (GBP) regimen versus placebo on opioid consumption, pain scores and knee flexion, as well as adverse effects, after total knee arthroplasty.http://dx.doi.org/10.1155/2009/930609
spellingShingle Hance Clarke
Sara Pereira
Deborah Kennedy
Ian Gilron
Joel Katz
Jeffrey Gollish
Joseph Kay
Gabapentin Decreases Morphine Consumption and Improves Functional Recovery following Total Knee Arthroplasty
Pain Research and Management
title Gabapentin Decreases Morphine Consumption and Improves Functional Recovery following Total Knee Arthroplasty
title_full Gabapentin Decreases Morphine Consumption and Improves Functional Recovery following Total Knee Arthroplasty
title_fullStr Gabapentin Decreases Morphine Consumption and Improves Functional Recovery following Total Knee Arthroplasty
title_full_unstemmed Gabapentin Decreases Morphine Consumption and Improves Functional Recovery following Total Knee Arthroplasty
title_short Gabapentin Decreases Morphine Consumption and Improves Functional Recovery following Total Knee Arthroplasty
title_sort gabapentin decreases morphine consumption and improves functional recovery following total knee arthroplasty
url http://dx.doi.org/10.1155/2009/930609
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