Evaluating the immune effector functions induced by humanized anti-CD99 antibody in eliminating T lymphoblastic leukemia/lymphoma cells

Abstract Monoclonal antibodies (mAbs) have emerged as targeted immunotherapies with clinical effectiveness and low adverse effects for various cancers. However, antibody drugs for treating aggressive T cell malignancies, T lymphoblastic leukemia/lymphoma (T-ALL/T-LBL), are still limited. Therefore,...

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Main Authors: Kamonporn Kotemul, Ratthakorn Chaiwut, Chaochetdhapada Putpim, Supansa Pata, Witida Laopajon, Chatchai Tayapiwatana, Watchara Kasinrerk, Nuchjira Takheaw
Format: Article
Language:English
Published: Springer 2025-04-01
Series:Discover Oncology
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Online Access:https://doi.org/10.1007/s12672-025-02281-0
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