Unravelling the transcriptomic landscape of primary lymphocytic scarring alopecias: systematic review and meta-analysis

Unravelling the transcriptomic landscape of primary lymphocytic scarring alopecias: systematic review and meta-analysis

Primary lymphocytic scarring alopecias (PLSAs)—including frontal fibrosing alopecia (FFA), lichen planopilaris (LPP), and central centrifugal cicatricial alopecia (CCCA)—are chronic inflammatory scalp disorders leading to irreversible follicular destruction. Despite overlapping histopathology, their...

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Main Authors: Irene Rivera-Ruiz, Benjamin Ungar, Viviana Dávila-Flores, Jesús Gay-Mimbrera, Pedro J. Gómez-Arias, Miguel Juan-Cencerrado, Carmen Mochón-Jiménez, Esmeralda Parra-Peralbo, Beatriz Isla-Tejera, Teresa López-Viñau López, Emma Guttman-Yassky, Juan Ruano
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Immunology
Subjects:
scarring alopecia
frontal fibrosing alopecia
lichen planopilaris
central centrifugal cicatricial alopecia
transcriptome meta-analysis
interferon-gamma
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1651019/full
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https://www.frontiersin.org/articles/10.3389/fimmu.2025.1651019/full

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