Associations of DNA Methylation Algorithms of Aging With Cardiovascular Disease and Mortality Risk Among US Older Adults

Associations of DNA Methylation Algorithms of Aging With Cardiovascular Disease and Mortality Risk Among US Older Adults

Background Several DNA methylation (DNAm) algorithms have recently emerged as robust predictors of aging and adverse health outcomes in older adults, offering valuable insights into cardiovascular disease (CVD) risk stratification. However, their predictive performance for CVD varies significantly....

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Bibliographic Details
Main Authors: Xian Cui, Shiqun Sun, Hui Zhang, Yulu Gong, Darong Hao, Yaqian Xu, Chongyu Ding, Jing Wang, Tongyan An, Jinlong Liu, Jun Du, Xiangwei Li
Format: Article
Language:English
Published: Wiley 2025-05-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
age acceleration
CVD mortality risk
CVD risk
DNA methylation
epigenetic clock
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.124.040374
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https://www.ahajournals.org/doi/10.1161/JAHA.124.040374

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