Nrf2 depletion enhanced curcumin therapy effect in gastric cancer by inducing the excessive accumulation of ROS

Abstract Gastric cancer (GC) is the most common malignant tumor of the gastrointestinal tract and currently has a poor clinical outcome. Turmeric’s rhizome contains a polyphenolic component called curcumin (Cur), which has been demonstrated to inhibit a variety of tumor cells, such as pancreatic, co...

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Bibliographic Details
Main Authors: Yan Wang, Shasha Wang, Chenchen Ma, Weiwei Qi, Jing Lv, Mengqi Zhang, Shibo Wang, Rui Wang, Yangyang Lu, Wensheng Qiu
Format: Article
Language:English
Published: Nature Portfolio 2024-12-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-024-81375-1
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