Decellularized liver scaffolds for constructing drug-metabolically functional ex vivo human liver models

Decellularized liver scaffolds for constructing drug-metabolically functional ex vivo human liver models

The creation of ex vivo human liver models has long been a critical objective in academic, clinical, and pharmaceutical research, particularly for drug development, where accurate evaluation of hepatic metabolic dynamics is crucial. We have developed a bioengineered, perfused, organ-level human live...

Full description

Saved in:
Bibliographic Details
Main Authors: Juan Liu, Ariel Hanson, Wenzhen Yin, Qiao Wu, Eliane Wauthier, Jinmei Diao, Timothy Dinh, Jeff Macdonald, Ruihong Li, Masahiko Terajima, Mitsuo Yamauchi, Ziye Chen, Praveen Sethupathy, Jiahong Dong, Lola M. Reid, Yunfang Wang
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2025-01-01
Series:Bioactive Materials
Subjects:
Human tissue engineered liver
Liver biomatrix scaffolds
Metabolism
Drug-induced liver injury
Online Access:http://www.sciencedirect.com/science/article/pii/S2452199X24004328
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

http://www.sciencedirect.com/science/article/pii/S2452199X24004328

Similar Items