SRPK1 is a significant factor in driving the progression of diabetic kidney fibrosis

Abstract Background Diabetic nephropathy leads to renal fibrosis via excessive ECM accumulation. Current therapies lack specificity, highlighting the need to identify targets like SRPK1, whose role in diabetic kidney fibrosis remains unclear. Methods We investigated SRPK1’s function using a streptoz...

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Bibliographic Details
Main Authors: Shichao Han, Shuaijun Ma, Kepu Liu, Ruochen Qi, Guohui Wang, Weijun Qin, Xutao Zhang
Format: Article
Language:English
Published: BMC 2025-08-01
Series:Diabetology & Metabolic Syndrome
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Online Access:https://doi.org/10.1186/s13098-025-01889-0
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