HMOS 2’FL and 3FL prevent house dust mite induced proinflammatory cytokine release in vitro and decrease specific IgE production in a murine allergic asthma model

HMOS 2’FL and 3FL prevent house dust mite induced proinflammatory cytokine release in vitro and decrease specific IgE production in a murine allergic asthma model

IntroductionAllergic asthma is characterized by sensitization to airborne allergens like house dust mite (HDM). Human milk oligosaccharides (HMOS) are linked to improved immune maturation and potentially alleviate allergy development.MethodsA human in vitro model for crosstalk between bronchial epit...

Full description

Saved in:
Bibliographic Details
Main Authors: Marit Zuurveld, Janna W. M. de Kleer, Alinda J. Berends, Manou M. Kooy, Ingrid Van Ark, Thea Leusink-Muis, Nienke Kettelarij, Gert Folkerts, Johan Garssen, Belinda van’t Land, Linette E. M. Willemsen
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-02-01
Series:Frontiers in Nutrition
Subjects:
advanced in vitro models
allergic asthma
human milk oligosaccharides
mucosal inflammation
allergy prevention
Online Access:https://www.frontiersin.org/articles/10.3389/fnut.2025.1491430/full
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://www.frontiersin.org/articles/10.3389/fnut.2025.1491430/full

Similar Items