Transcriptomic analysis of Myxococcus xanthus csgA, fruA, and mrpC mutants reveals extensive and diverse roles of key regulators in the multicellular developmental process

Transcriptomic analysis of Myxococcus xanthus csgA, fruA, and mrpC mutants reveals extensive and diverse roles of key regulators in the multicellular developmental process

Abstract Background The bacterium Myxococcus xanthus provides an important multicellular model for understanding stress responses. The regulatory proteins CsgA, FruA, and MrpC are essential to survive prolonged starvation by forming fruiting bodies, which are mounds containing hardy round spores for...

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Bibliographic Details
Main Authors: Mark A. Farrugia, Ramya Rajagopalan, Lee Kroos
Format: Article
Language:English
Published: BMC 2025-04-01
Series:BMC Genomics
Subjects:
Bacterial development
Gene regulation
Transcriptomics
Myxococcus xanthus
CsgA
FruA
Online Access:https://doi.org/10.1186/s12864-025-11417-z
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https://doi.org/10.1186/s12864-025-11417-z

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