Next-generation immunotherapeutic approaches for blood cancers: Exploring the efficacy of CAR-T and cancer vaccines

Next-generation immunotherapeutic approaches for blood cancers: Exploring the efficacy of CAR-T and cancer vaccines

Abstract Recent advancements in immunotherapy, particularly Chimeric antigen receptor (CAR)-T cell therapy and cancer vaccines, have significantly transformed the treatment landscape for leukemia. CAR-T cell therapy, initially promising in hematologic cancers, faces notable obstacles in solid tumors...

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Main Authors: Kiavash Hushmandi, Abbas Ali Imani Fooladi, Russel J. Reiter, Najma Farahani, Liping Liang, Amir Reza Aref, Noushin Nabavi, Mina Alimohammadi, Le Liu, Gautam Sethi
Format: Article
Language:English
Published: BMC 2025-05-01
Series:Experimental Hematology & Oncology
Subjects:
Leukemias
Immunotherapy
Cancer vaccines
CAR-T cell therapy
Immune evasion
Online Access:https://doi.org/10.1186/s40164-025-00662-3
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https://doi.org/10.1186/s40164-025-00662-3

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