Ectopic fat accumulation in human astrocytes impairs insulin action

Ectopic fat accumulation in human astrocytes impairs insulin action

Astrocytes provide neurons with structural support and energy in form of lactate, modulate synaptic transmission, are insulin sensitive and act as gatekeeper for water, ions, glutamate and second messengers. Furthermore, astrocytes are important for glucose sensing, possess neuroendocrine functions...

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Main Authors: Martin Heni, Sabine S. Eckstein, Jens Schittenhelm, Anja Böhm, Norbert Hogrefe, Martin Irmler, Johannes Beckers, Martin Hrabě de Angelis, Hans-Ulrich Häring, Andreas Fritsche, Harald Staiger
Format: Article
Language:English
Published: The Royal Society 2020-09-01
Series:Royal Society Open Science
Subjects:
astrocyte
human
insulin
lipid storage
Online Access:https://royalsocietypublishing.org/doi/10.1098/rsos.200701
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https://royalsocietypublishing.org/doi/10.1098/rsos.200701

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