Deciphering a profiling based on multiple post-translational modifications functionally associated regulatory patterns and therapeutic opportunities in human hepatocellular carcinoma

Deciphering a profiling based on multiple post-translational modifications functionally associated regulatory patterns and therapeutic opportunities in human hepatocellular carcinoma

Abstract Background Posttranslational modifications (PTMs) play critical roles in hepatocellular carcinoma (HCC). However, the locations of PTM-modified sites across protein secondary structures and regulatory patterns in HCC remain largely uncharacterized. Methods Total proteome and nine PTMs (phos...

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Bibliographic Details
Main Authors: Yuanxiang Lao, Yirong Jin, Songfeng Wu, Ting Fang, Qiang Wang, Longqin Sun, Beicheng Sun
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Molecular Cancer
Subjects:
Hepatocellular carcinoma
Posttranslational modification
Nucleolin
Alternative splicing
Online Access:https://doi.org/10.1186/s12943-024-02199-1
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https://doi.org/10.1186/s12943-024-02199-1

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