Neutrophilic inflammation in sputum or blood does not define a clinically distinct asthma phenotype in ATLANTIS

Neutrophilic inflammation in sputum or blood does not define a clinically distinct asthma phenotype in ATLANTIS

Introduction Neutrophilic asthma has been suggested to be a clinically distinct phenotype characterised by more severe airflow obstruction and higher exacerbation risk. However, this has only been assessed in few and smaller studies, using different cut-offs to define neutrophilia, and with conflict...

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Main Authors: Pauline J.M. Kuks, Tessa M. Kole, Monica Kraft, Salman Siddiqui, Leonardo M. Fabbri, Klaus F. Rabe, Alberto Papi, Chris Brightling, Dave Singh, Thys van der Molen, Jan Willem W.H. Kocks, Kian Fan Chung, Ian M. Adcock, Pankaj K. Bhavsar, Nazanin Zounemat Kermani, Irene H. Heijink, Simon D. Pouwels, Huib A.M. Kerstjens, Dirk-Jan Slebos, Maarten van den Berge
Format: Article
Language:English
Published: European Respiratory Society 2025-02-01
Series:ERJ Open Research
Online Access:http://openres.ersjournals.com/content/11/1/00616-2024.full
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http://openres.ersjournals.com/content/11/1/00616-2024.full

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