Emergence of planar cell polarity from the interplay of local interactions and global gradients

Emergence of planar cell polarity from the interplay of local interactions and global gradients

Planar cell polarity (PCP) – tissue-scale alignment of the direction of asymmetric localization of proteins at the cell-cell interface – is essential for embryonic development and physiological functions. Abnormalities in PCP can result in developmental imperfections, including neural tube closure d...

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Bibliographic Details
Main Authors: Divyoj Singh, Sriram Ramaswamy, Mohit Kumar Jolly, Mohd Suhail Rizvi
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2024-10-01
Series:eLife
Subjects:
planar cell polarity
domineering non-autonomy
tissue-level gradients
asymmetric localization
pattern formation
inter-cellular hetero-dimer
Online Access:https://elifesciences.org/articles/84053
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