Connexin46 in the nucleus of cancer cells: a possible role as transcription modulator

Connexin46 in the nucleus of cancer cells: a possible role as transcription modulator

Abstract Background Oncogenes drive cancer progression, but few are active exclusively in tumor cells. Connexins (Cxs), traditionally recognized as ion channel proteins, can localize to the nucleus and regulate gene expression, playing key roles in both physiological and pathological processes. Cx46...

Full description

Saved in:
Bibliographic Details
Main Authors: Ainoa Fernández-Olivares, Viviana P Orellana, Jesús Llanquinao, Gonzalo Nuñez, Pablo Pérez-Moreno, Sebastián Contreras-Riquelme, Alberto JM Martin, Fabio Mammano, Ivan E Alfaro, Juan F Calderón, Jimmy Stehberg, Mauricio A Sáez, Mauricio A. Retamal
Format: Article
Language:English
Published: BMC 2025-03-01
Series:Cell Communication and Signaling
Subjects:
Connexin46
Transcription factor
Cancer
IRES
Online Access:https://doi.org/10.1186/s12964-025-02151-w
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doi.org/10.1186/s12964-025-02151-w

Similar Items