Single-cell profiling aligns CD56bright and cytomegalovirus-induced adaptive natural killer cells to a naïve-memory relationship

Single-cell profiling aligns CD56bright and cytomegalovirus-induced adaptive natural killer cells to a naïve-memory relationship

Development of antigen-specific memory upon pathogen exposure is a hallmark of the adaptive immune system. While natural killer (NK) cells are considered part of the innate immune system, humans exposed to the chronic viral pathogen cytomegalovirus (CMV) often possess a distinct NK cell population l...

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Bibliographic Details
Main Authors: M. Kazim Panjwani, Simon Grassmann, Rosa Sottile, Jean-Benoît Le Luduec, Theodota Kontopoulos, Kattria van der Ploeg, Joseph C. Sun, Katharine C. Hsu
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-12-01
Series:Frontiers in Immunology
Subjects:
natural killer cell (NK cells)
HCMV (human cytomegalovirus)
lymphocyte development and function
innate memory
single-cell RNA (scRNA) sequencing
human immunology
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1499492/full
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https://www.frontiersin.org/articles/10.3389/fimmu.2024.1499492/full

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