NMR based clinical metabolomics revealed altered lipid and sugar metabolism in systemic sclerosis with implications for diagnosis and therapeutic strategies

NMR based clinical metabolomics revealed altered lipid and sugar metabolism in systemic sclerosis with implications for diagnosis and therapeutic strategies

Abstract Systemic Sclerosis (SSc) is a complex autoimmune disorder characterized by vascular dysfunction, immune dysregulation, and progressive fibrosis of the skin and internal organs. Despite substantial research, its pathophysiology remains enigmatic, necessitating the identification of altered m...

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Main Authors: Gurvinder Singh, Sakir Ahmed, Durgesh Dubey, Mohit Kumar Rai, Atul Rawat, Vikas Agarwal, Dinesh Kumar
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Scientific Reports
Subjects:
NMR based metabolomics
Systemic sclerosis
Inositol pathway, mannosylation
Circulatory biomarkers
Online Access:https://doi.org/10.1038/s41598-025-16493-5
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https://doi.org/10.1038/s41598-025-16493-5

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