LGALS3BP/90K suppresses porcine reproductive and respiratory syndrome virus replication by enhancing GP3 degradation and stimulating innate immunity

LGALS3BP/90K suppresses porcine reproductive and respiratory syndrome virus replication by enhancing GP3 degradation and stimulating innate immunity

Abstract Porcine reproductive and respiratory syndrome virus (PRRSV) seriously affects the world pig industry, and existing vaccines are not enough to protect against PRRSV efficiently. Identifying host factors that inhibit PRRSV infection may provide potential targets for antiviral therapies. Galec...

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Bibliographic Details
Main Authors: Qingyu Fan, Haiyan Wang, Hanze Liu, Jinzhi Li, Juan Huang, Ying Yu, Zhi Cao, Qiaoya Zhang
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Veterinary Research
Subjects:
PRRSV
LGALS3BP/90K
viral replication
proteasomal degradation
innate immunity
Online Access:https://doi.org/10.1186/s13567-025-01556-2
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https://doi.org/10.1186/s13567-025-01556-2

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