The role of IP3 receptors and SERCA pumps in restoring working memory under amyloid β induced Alzheimer's disease: a modeling study
Memory impairment is a prevalent symptom in patients with Alzheimer's disease (AD), with working memory loss being the most prominent deficit. Recent experimental evidence suggests that abnormal calcium levels in the Endoplasmic Reticulum (ER) may disrupt synaptic transmission, leading to memor...
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| Main Authors: | Ziyi Huang, Lei Wang |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2025-07-01
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| Series: | Frontiers in Computational Neuroscience |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fncom.2025.1643547/full |
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