Integrative genomic analysis and diagnostic modeling of osteoporosis: unraveling the interplay of autophagy, osteogenesis, adipogenesis, and immune infiltration

Integrative genomic analysis and diagnostic modeling of osteoporosis: unraveling the interplay of autophagy, osteogenesis, adipogenesis, and immune infiltration

BackgroundOsteoporosis (OP), marked by reduced bone density and structural decay, poses a heightened risk of fractures. Our study formulates a predictive diagnostic model for OP by analyzing differential gene expression, thereby improving early diagnosis and therapeutic approaches.MethodsUsing GSE62...

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Bibliographic Details
Main Authors: Lin-Jing Han, Jian-Zong Zhu, Hong-Cai Liu, Xiao-Sheng Lin, Shu-Zhong Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Medicine
Subjects:
osteoporosis
bioinformatics
autophagyosteogenesis
immune infiltration
diagnostic biomarkers
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2025.1544390/full
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https://www.frontiersin.org/articles/10.3389/fmed.2025.1544390/full

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