Differed brain spontaneous neural activity between limb-onset and bulbar-onset amyotrophic lateral sclerosis patients

Differed brain spontaneous neural activity between limb-onset and bulbar-onset amyotrophic lateral sclerosis patients

Purpose: To investigate the differences in brain spontaneous neural activity between limb-onset and bulbar-onset amyotrophic lateral sclerosis (ALS-L and ALS-B, respectively) patients using resting-state functional MRI (rs-fMRI) with amplitude of low-frequency fluctuation (ALFF) and regional homogen...

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Bibliographic Details
Main Authors: Si-Jie Chen, Qing-Yang Li, Jiang Zhou, Qian Wu, Yu Zhang, Qian-Qian Zhang, Hao Hu, Xiao-Quan Xu, Fei-Yun Wu, Qi Niu
Format: Article
Language:English
Published: Elsevier 2025-02-01
Series:Brain Research Bulletin
Subjects:
Amyotrophic lateral sclerosis
Bulbar-onset
Limb-onset
Resting-state functional magnetic resonance imaging
Amplitude of low-frequency fluctuation
Regional homogeneity
Online Access:http://www.sciencedirect.com/science/article/pii/S0361923025000413
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