Dendritic cell-derived MYD88 potentiates as a biomarker for immune regulation in hepatocellular carcinoma and may predict a better immunological result

Dendritic cell-derived MYD88 potentiates as a biomarker for immune regulation in hepatocellular carcinoma and may predict a better immunological result

IntroductionMYD88 (myeloid differentiation primary response 88) is a key adaptor protein mediate immune responses, primarily through Toll-like receptors (TLRs) and interleukin-1 receptor (IL-1R) signaling. The TLR/MYD88 pathway plays a critical role in dendritic cells (DC) maturation and function, c...

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Bibliographic Details
Main Authors: Zheming Liu, Hengbo Zhu, Fengxia Zhang, Wenting Huang, Shipeng Zhu, Songjiang He, Yi Yao, Qibin Song, Xue Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-03-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
dendritic cells
MyD88
hepatocellular carcinoma
TME
immunotherapy
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2025.1554705/full
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https://www.frontiersin.org/articles/10.3389/fcell.2025.1554705/full

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