Assessing CometChip technology for DNA damage studies in non-model species: distinct UV-induced responses in turtles and mammals

Assessing CometChip technology for DNA damage studies in non-model species: distinct UV-induced responses in turtles and mammals

Abstract Objective We evaluated the feasibility of using the high-throughput CometChip to assess DNA damage in non-model species. Specifically, we measured UVA-induced damage in fibroblasts from five turtle and four mammalian species with diverse life histories and cancer rates. Results Turtles exhi...

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Bibliographic Details
Main Authors: Stephanie E. Bulls, Elijah Finn, Peter Sykora, Vincent J. Lynch, Paramahansa Pramanik, Scott Glaberman, Ylenia Chiari
Format: Article
Language:English
Published: BMC 2025-06-01
Series:BMC Research Notes
Subjects:
Comet assay
Oxidative stress
Aging
Longevity
Cancer
Comparative oncology
Online Access:https://doi.org/10.1186/s13104-025-07285-1
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https://doi.org/10.1186/s13104-025-07285-1

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