Antidepressant Effects of Ginsenosides from Panax notoginseng

Antidepressant Effects of Ginsenosides from Panax notoginseng

Ginsenosides Rg1, Rb1, R1, Rd, and Re are major constituents of Panax notoginseng, a famous traditional Chinese medicinal herb, which has both stimulative and inhibitory effects on the central nervous system (CNS). The monoamine hypothesis proposes that depression is a result of the depletion of 5-h...

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Bibliographic Details
Main Authors: Yang YAO, Wei SANG, Xiu-shi YANG, Mei-jing ZHAI, Li-li WANG, Pei-you QIN, Li WU, Xian-rong ZHOU, Li-jun WANG, Jin-yan LI, Zhi-hua ZHU, Gui-xing REN
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2012-03-01
Series:Journal of Integrative Agriculture
Subjects:
Panax notoginseng saponins
forced swimming
tail suspension
antidepressant-like effect
monoamine
Online Access:http://www.sciencedirect.com/science/article/pii/S2095311912600343
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