Genomic and transcriptomic landscapes of metastatic neuroendocrine neoplasms from distinct primary sites and their clinical implications

Genomic and transcriptomic landscapes of metastatic neuroendocrine neoplasms from distinct primary sites and their clinical implications

Abstract Neuroendocrine neoplasms (NENs) encompass a highly heterogeneous group of neoplasms with varying prognoses and molecular alterations. Molecular profiling studies have furthered our understanding of NENs, but the majority of previous studies have focused on primary tumors and on mutational l...

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Bibliographic Details
Main Authors: Kathleen Wee, Kevin C. Yang, David F. Schaeffer, Chen Zhou, Emily Leung, Xiaolan Feng, Janessa Laskin, Marco A. Marra, Jonathan M. Loree, Sharon M. Gorski
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Scientific Reports
Subjects:
Neuroendocrine neoplasms
Genomics
Personalized medicine
Transcriptomics
Cancer genomics
Online Access:https://doi.org/10.1038/s41598-025-00549-7
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https://doi.org/10.1038/s41598-025-00549-7

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