YAP and ECM Stiffness: Key Drivers of Adipocyte Differentiation and Lipid Accumulation

ECM stiffness significantly influences the differentiation of adipose-derived stem cells (ADSCs), with YAP—a key transcription factor in the Hippo signaling pathway—playing a pivotal role. This study investigates the effects of ECM stiffness on ADSC differentiation and its relationship with YAP sign...

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Bibliographic Details
Main Authors: Da-Long Dong, Guang-Zhen Jin
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/13/22/1905
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