Revealing long-range heterogeneous organization of nucleoproteins with 6mA footprinting by ipdTrimming

Abstract Enabled by long-read sequencing technologies, particularly Single Molecule, Real-Time sequencing, N6-methyladenine (6mA) footprinting is a transformative methodology for revealing the heterogenous and dynamic distribution of nucleosomes and other DNA-binding proteins. Here, we present ipdTr...

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Bibliographic Details
Main Authors: Wentao Yang, Xue Qing Wang, Fan Wei, Jingqi Yu, Yifan Liu, Yali Dou
Format: Article
Language:English
Published: BMC 2025-05-01
Series:Genome Biology
Online Access:https://doi.org/10.1186/s13059-025-03592-9
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