Context-Dependent Regulation of Autophagy by IKK-NF-κB Signaling: Impact on the Aging Process

The NF-κB signaling system and the autophagic degradation pathway are crucial cellular survival mechanisms, both being well conserved during evolution. Emerging studies have indicated that the IKK/NF-κB signaling axis regulates autophagy in a context-dependent manner. IKK complex and NF-κB can enhan...

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Bibliographic Details
Main Authors: Antero Salminen, Juha M. T. Hyttinen, Anu Kauppinen, Kai Kaarniranta
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:International Journal of Cell Biology
Online Access:http://dx.doi.org/10.1155/2012/849541
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