3D bioprinted dynamic bioactive living construct enhances mechanotransduction-assisted rapid neural network self-organization for spinal cord injury repair

3D bioprinted dynamic bioactive living construct enhances mechanotransduction-assisted rapid neural network self-organization for spinal cord injury repair

Biomimetic neural substitutes, constructed through the bottom-up assembly of cell-matrix modulus via 3D bioprinting, hold great promise for neural regeneration. However, achieving precise control over the fate of neural stem cells (NSCs) to ensure biological functionality remains challenging. Cell b...

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Bibliographic Details
Main Authors: Jia Yang, Kunkoo Kim, Yaosai Liu, Xiaobin Luo, Chao Ma, Weitao Man, Yating Zhao, Zheng Cao, Peilun Hu, Junlin Chen, Yu Wang, Xiaodan Sun, Lingyun Zhao, Guihuai Wang, Kaiyuan Yang, Xiumei Wang
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2025-04-01
Series:Bioactive Materials
Subjects:
3D bioprinting
Dynamic bioink
Neural stem cells
Cell-instructive cues
Spinal cord injury
Online Access:http://www.sciencedirect.com/science/article/pii/S2452199X24005656
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