Confirmation of HLA-II associations with TB susceptibility in admixed African samples

Confirmation of HLA-II associations with TB susceptibility in admixed African samples

Previously, the International Tuberculosis Host Genetics Consortium (ITHGC) demonstrated the power of large-scale GWAS analysis across diverse ancestries in identifying tuberculosis (TB) susceptibility loci (Schurz et al., 2024). Despite identifying a significant genetic correlate in the human leuko...

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Bibliographic Details
Main Authors: Dayna Adrienne Croock, Yolandi Swart, Haiko Schurz, Desiree C Petersen, Marlo Möller, Caitlin Uren
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2025-06-01
Series:eLife
Subjects:
human leukocyte antigen
tuberculosis
local ancestry
admixture
KhoeSan
Online Access:https://elifesciences.org/articles/99200
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https://elifesciences.org/articles/99200

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