Fucoidan alleviates high sucrose-induced metabolic disorders and enhances intestinal homeostasis through modulation of Notch signaling

Fucoidan alleviates high sucrose-induced metabolic disorders and enhances intestinal homeostasis through modulation of Notch signaling

Introduction: The therapeutic potential of fucoidan (FUC), a natural polysaccharide, in metabolic disorders is recognized, yet its underlying mechanisms remain unclear. Methods: We conducted investigations into the therapeutic mechanisms of FUC sourced from Sargassum fulvellum concerning metabolic d...

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Main Authors: Jian Liu, Weiqiang Xia, Qifang Wu, Ya Zhang, Yu Wu, Boyang Li, Fangyu Chen, Xueting Du, Siya Wu, Yue Yang, Yitian Gao, Mingjiang Wu, Laijin Su, Haibin Tong
Format: Article
Language:English
Published: Elsevier 2025-05-01
Series:Journal of Advanced Research
Subjects:
Fucoidan
Sulfate group
Metabolic disorders
Intestinal homeostasis
Gut hormones
Notch signaling
Online Access:http://www.sciencedirect.com/science/article/pii/S2090123224002248
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